Dynamic Nanopore Assembly

Title:
Dynamic Nanopore Assembly

Schedule:
Date: 16 Jan 2023 (Mon)
Time: 18:00 - 19:00 (HKT)

Venue:
CYPP3

Speaker: 
Prof. Myongsoo Lee
Department of Chemistry
Fudan University

Abstract: 

In this Seminar, the speaker will introduce the results on how to construct dynamic self-assembled nanopore structures performing various functions in response to external forces. For example, synthetic tubular pores are able to undergo open-closed gating driven by an external signal, which function as an artificial enzyme. When self-assembled tubules embed DNA inside the hollow cavities, the complex assembly undergoes collective motion in helicity switching. In the case of toroid assembly, the static toroids are able to undergo spontaneous helical growth when they are fueled by thermal energy. The helical growing drives actuation of spherical vesicles into tubular vesicles, reminiscent of microtubules. Moving from 1-D to 2-D structures, the internal pores are able to form discrete chiral interior which performs precise chiral separation and chiral macrocyclizations. The speaker will discuss these examples of the dynamic pore structures with their complex functions.

- ALL ARE WELCOME -